MyBioSource.com's KLHL21 Conjugated Antibody is a Mouse monoclonal antibody. The KLHL21 Conjugated Antibody was generated using KLHL21 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Other.
Description
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR (KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR (KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome